Treatment of Hypertrophic Cardiomyopathy: What Every Cardiologist Needs to Know - American College of Cardiology (2023)

Hypertrophic cardiomyopathy (HCM) is an inherited disease of the cardiac sarcomere that results in left ventricular hypertrophy, hyperdynamic function, microvascular dysfunction, impaired relaxation, and myocardial fibrosis.1 Clinical hallmarks include left ventricular outflow tract obstruction (LVOTO), arrhythmias, and heart failure.2,3 To date, no disease-modifying therapies have been identified, although clinical trials of novel therapeutics are in progress.4,5 This analysis focuses on HCM management strategies fundamental to the care of patients with HCM: LVOTO, sudden cardiac death (SCD), atrial fibrillation, exercise restriction, and heart failure.

Medical Therapy

A significant proportion of HCM patients suffer from LVOTO; therefore, investigating obstruction with both resting echo (with Valsalva) and stress echo if the gradient is below 50mmHg on rest interrogation should be performed. Treatment of obstruction is indicated for symptomatic patients (NYHA Class > II) and medical therapy is the first-line approach.6 Importantly, patients may become accustomed to their reduced functional capacity and minimize symptoms,7 making objective confirmation of functional capacity with cardiopulmonary exercise testing a useful adjunct to history-taking for assessment of exertional intolerance.8,9 Medical therapies include beta-blockade and verapamil alone or in combination, though verapamil may increase LVOTO-associated symptoms in some individuals due to its vasodilatory effect.10 Disopyramide may be added for patients with symptoms refractory to the use of beta-blocker or calcium channel blocker therapy.10

Invasive Therapy

(Video) Hypertrophic Cardiomyopathy: Advanced Treatment Options

Septal reduction therapy (SRT) is indicated when medical therapy fails to control NYHA Class III symptoms or following LVOTO-associated syncope or near syncope refractory to medical therapy. There are two forms of SRT: surgical myomectomy11,12 and alcohol septal ablation. Surgical myectomy provides definitive therapy for symptomatic LVOTO and is associated with low post-operative mortality and morbidity when carried out by experienced operators in expert centers, although no significant long-term mortality benefit has been demonstrated.2 Given this, pre-operative counseling should emphasize that the benefit is currently limited to symptom improvement.

With refinement of the techniques and greater experience, post-procedural outcomes following alcohol septal ablation are comparable to surgical myectomy in appropriately selected patients at expert centers.7 Selecting the right approach to SRT is challenging and should include not only the assessment of provider and center expertise, but also factors such as patient age, comorbid disease, and patient preference.2 Despite excellent intermediate and long-term results, some patients remain symptomatic or develop heart failure after SRT.13

Sudden Death

Patients with HCM are at increased risk for SCD, and risk stratification for implantable cardioverter defibrillator (ICD) implantation is critical in this population. Primary prevention with an ICD is reasonable for patients with severe hypertrophy (>30mm), family history of sudden death in a first degree relative, recent unexplained syncope, or "burnt-out" HCM (LVEF < 50%).2,6,7 The presence of non-sustained ventricular tachycardia on 24-hour Holter or abnormal blood pressure response to exercise, when added to other risk factors, also supports primary prevention ICD.14 Other risk factors that may influence the decision to place an ICD for primary prevention include marked late-gadolinium enhancement on magnetic resonance imaging (MRI) (>15%), the presence of an apical aneurysm, and some genetic mutations present in families with high prevalence of sudden cardiac death.3,6,7,15-17 Secondary prevention with ICD placement in those surviving SCD or with sustained ventricular tachycardia (VT) is universally recommended.6 In the case of syncope, a thorough evaluation for provoked obstruction is first required to avoid ICD implantation for syncope related to LVOTO rather than ventricular arrhythmias.7 Periodic reassessment of risk factors is recommended as part of ongoing follow up, with more frequent testing reserved for younger patients and those with borderline risk factors.

(Video) Hypertrophic Cardiomyopathy: The Most Interesting Heart Disease

Atrial Fibrillation

Atrial fibrillation can worsen exertional symptoms and increase stroke risk in patients with HCM.2 The role for catheter ablation has not been specifically studied in HCM cohorts but remains an option for patients with symptoms refractory to medical therapy.18 As refractory symptomatic atrial fibrillation often marks progressive disease with restrictive physiology, these patients also warrant evaluation for advanced heart failure therapies such as heart transplantation.19 Due to the increased risk for thromboembolism in HCM patients who develop atrial fibrillation or flutter, oral anticoagulation is recommended as primary stroke prophylaxis regardless of CHA2DS2-VASc score.6


Balancing the overall benefits of exercise in the general population with the potential risk of SCD in the HCM population is a challenge. Strenuous exercise has been routinely discouraged,6 though there is an increasing appreciation for how the health benefits of exercise should be balanced with the potential risks.20 Studies to better define the risk of high-intensity exercise in HCM are ongoing (LIVE-HCM/LQT), and thoughtful discussion with shared decision making is a widely accepted strategy for application of exercise restrictions in this population.

(Video) ACC Cardiology Hour With Dr. Valentin Fuster | ACC.22 Day 1

Heart Failure

Some patients with HCM develop clinical heart failure, ranging from heart failure with preserved ejection fraction, to severe restrictive cardiomyopathy, to 'burnt-out' dilated hypertrophic cardiomyopathy.2 Patients diagnosed with HCM prior to age 40 have more than a 60% chance of experiencing clinical heart failure by age 70, and those diagnosed between ages 40 and 60 have greater than a 40% chance to experience heart failure by that age. However, only 5% of HCM patients will progress to require advanced heart failure therapies during their lifetime.21

Given the predominant restrictive physiology with fixed stroke volume and small left ventricular cavity, patients often do not respond to inotropic support or benefit from implantation of a durable left ventricular assist device (LVAD). This is reflected in the 2018 United Network for Organ Sharing (UNOS) allocation guidelines for heart transplantation, which affords HCM patients higher outpatient priority listing at Status 4 than other outpatient transplant candidates with ischemic or dilated cardiomyopathy, who are Status 6.22

What's on the Horizon?

(Video) Hypertrophic Cardiomyopathy: Current Understanding and Knowledge Gaps, April 26th, 2019

There are currently no medical interventions that alter the natural course of HCM, but cardiac myosin inhibitors have shown potential promise.4,5 Trials investigating the effect of cardiac myosin inhibitors such as mavacamten (EXPLORER-HCM and MAVERICK-HCM) and CK-274 (REDWOOD-HCM) on LVOTO and HCM associated diastolic heart failure are underway. Finally, gene-silencing with CRISPR/Cas9 gene-editing technology may someday play a role in the prevention of disease development before the appearance of clinical manifestations.23

In summary, patients with HCM may suffer from LVOTO obstruction, atrial arrhythmias, SCD, and advanced heart failure. Current therapies focus on the disease manifestations, but future therapies may offer hope to effectively address the pathophysiology of HCM. Until then, recognition of the role of medical, interventional, device, and surgical therapies, and the use of shared decision making in areas of exercise prescription, are essential to improve the quality of life and survival of patients with HCM.


  1. Marian AJ, Braunwald E. Hypertrophic Cardiomyopathy: genetics, pathogenesis, clinical manifestations, diagnosis, and therapy. Circ Res 2017;121:749-70.
  2. Maron BJ, Ommen SR, Semsarian C, Spirito P, Olivotto I, Maron MS. Hypertrophic cardiomyopathy: present and future, with translation into contemporary cardiovascular medicine. J Am Coll Cardiol 2014;64:83-99.
  3. Semsarian C, Ingles J, Maron MS, Maron BJ. New perspectives on the prevalence of hypertrophic cardiomyopathy. J Am Coll Cardiol 2015;65:1249-54.
  4. Heitner SB, Jacoby D, Lester SJ, et al. Mavacamten treatment for obstructive hypertrophic cardiomyopathy: a clinical trial. Ann Intern Med 2019;170:741-48.
  5. Robertson LA, Armas DR, Robbie E, et al. A first in human study of the selective cardiac myosin inhibitor, CK-3773274. J Card Fail 2019;25:79-80.
  6. Gersh BJ, Maron BJ, Bonow RO, et al. 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2011;58:e212-e60.
  7. Sen-Chowdhry S, Jacoby D, Moon JC, McKenna WJ. Update on hypertrophic cardiomyopathy and a guide to the guidelines. Nat Rev Cardiol 2016;13:651-75.
  8. Shah JS, Esteban MT, Thaman R, et al. Prevalence of exercise-induced left ventricular outflow tract obstruction in symptomatic patients with non-obstructive hypertrophic cardiomyopathy. Heart 2008;94:1288-94.
  9. Jacoby D, McKenna WJ. Support for routine use of metabolic stress testing in hypertrophic cardiomyopathy. Am J Cardiol 2012;109:1534-35.
  10. Jacoby DL, DePasquale EC, McKenna WJ. Hypertrophic cardiomyopathy: diagnosis, risk stratification and treatment. CMAJ 2013;185:127-134.
  11. Hang D, Nguyen A, Schaff HV. Surgical treatment for hypertrophic cardiomyopathy: a historical perspective. Ann Cardiothorac Surg 2017;6:318-28.
  12. Maron BJ, Rowin EJ, Casey SA, et al. Risk stratification and outcome of patients with hypertrophic cardiomyopathy ≥60 years of age. Circulation 2013;127:585-93.
  13. Wu JJ, Seco M, Medi C, et al. Surgery for hypertrophic cardiomyopathy. Biophys Rev 2015;7117-25.
  14. Adabag AS, Casey SA, Kuskowski MA, Zenovich AG, Maron BJ. Spectrum and prognostic significance of arrhythmias on ambulatory Holter electrocardiogram in hypertrophic cardiomyopathy. J Am Coll Cardiol 2005;45:697-704.
  15. Trivedi A, Knight BP. ICD therapy for primary prevention in hypertrophic cardiomyopathy. Arrhythm Electrophysiol Rev 2016;5:188-96.
  16. Rowin EJ, Maron BJ, Haas TS, et al. Hypertrophic cardiomyopathy with left ventricular apical aneurysm: implications for risk stratification and management. J Am Coll Cardiol 2017;69:761-773.
  17. Green JJ, Berger JS, Kramer CM, Salerno M. Prognostic value of late gadolinium enhancement in clinical outcomes for hypertrophic cardiomyopathy. JACC Cardiovasc Imaging 2012;5:370-77.
  18. Providencia R, Elliott P, Patel K, et al. Catheter ablation for atrial fibrillation in hypertrophic cardiomyopathy: a systematic review and meta-Analysis. Heart 2016;102:1533-43.
  19. Siontis KC, Geske JB, Ong K, Nishimura RA, Ommen SR, Gersh BJ. Atrial fibrillation in hypertrophic cardiomyopathy: prevalence, clinical correlations, and mortality in a large high-risk population. J Am Heart Assoc 2014;3:1-8.
  20. Papoutsidakis N, Heitner S, Ingles J, et al. Participation in thrill-seeking activities by patients with hypertrophic cardiomyopathy: individual preferences, adverse events and physician attitude. Am Heart J 2019;214:28-35.
  21. Ho CY, Day SM, Ashley EA, et al. Genotype and lifetime burden of disease in hypertrophic cardiomyopathy: insights from the sarcomeric human cardiomyopathy registry (SHaRe). Circulation 2018;138:1387-98.
  22. Shah KS, Kittleson MM, Kobashigawa JA. Updates on Heart Transplantation. Curr Heart Fail Rep 2019;16:150-56.
  23. Repetti GG, Toepfer CN, Seidman JG, Seidman CE. Novel Therapies for Prevention and Early Treatment of Cardiomyopathies. Circ Res 2019;124:1536-50.
(Video) Current Strategies In Diagnosis And Management Of Hypertrophic Cardiomyopathy

Clinical Topics: Anticoagulation Management, Arrhythmias and Clinical EP, Cardiac Surgery, Cardiovascular Care Team, Heart Failure and Cardiomyopathies, Invasive Cardiovascular Angiography and Intervention, Noninvasive Imaging, Prevention, Anticoagulation Management and Atrial Fibrillation, Implantable Devices, SCD/Ventricular Arrhythmias, Atrial Fibrillation/Supraventricular Arrhythmias, Aortic Surgery, Cardiac Surgery and Arrhythmias, Cardiac Surgery and Heart Failure, Statins, Acute Heart Failure, Chronic Heart Failure, Heart Transplant, Mechanical Circulatory Support, Interventions and Imaging, Interventions and Structural Heart Disease, Interventions and Vascular Medicine, Magnetic Resonance Imaging

Keywords: Atrial Fibrillation, Disopyramide, Stroke Volume, Hypertrophy, Left Ventricular, Cardiac Myosins, Contrast Media, Calcium Channel Blockers, Cardiomyopathy, Dilated, Cardiomyopathy, Restrictive, Sarcomeres, Heart Failure, Diastolic, Gadolinium, Secondary Prevention, Risk Factors, Quality of Life, Verapamil, Patient Preference, Heart-Assist Devices, Outpatients, Prevalence, Follow-Up Studies, Blood Pressure, Defibrillators, Implantable, Cardiomyopathy, Hypertrophic, Death, Sudden, Cardiac, Benzylamines, Heart Failure, Uracil, Syncope, Heart Transplantation, Tachycardia, Ventricular, Catheter Ablation, Stroke, Thromboembolism, Primary Prevention, Aneurysm, Magnetic Resonance Imaging, Fibrosis, Counseling, Medical History Taking, Mutation, Risk Assessment, Anticoagulants, Longitudinal Studies, ACCGrantHypertrophicCardiomyopathy

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What type of cardiologist treats hypertrophic cardiomyopathy? ›

A cardiologist or pediatric cardiologist often diagnoses and treats HCM. You may also be referred to a cardiomyopathy center where the health care team has specialized training. HCM is diagnosed based on your medical history, family history, a physical exam and diagnostic test results.

Which treatment should you recommend for hypertrophic cardiomyopathy HCM )? ›

Medications to treat hypertrophic cardiomyopathy and its symptoms might include: Beta blockers such as metoprolol (Lopressor, Toprol-XL), propranolol (Inderal, Innopran XL) or atenolol (Tenormin) Calcium channel blockers such as verapamil (Verelan, Calan SR,) or diltiazem (Cardizem, Tiazac)

What is the new medical treatment for HCM? ›

The first disease-specific treatment, mavacamten (brand name Camzyos), is part of a new class of medications used to treat adult patients with symptomatic obstructive HCM by directly targeting the proteins that cause the heart to contract. This agent can lead to a dramatic improvement in symptoms.

What is the first-line treatment for hypertrophic cardiomyopathy? ›

Beta-Blockers: Beta-blockers are recommended as first-line drug therapy in both obstructive and nonobstructive symptomatic HCM. Beta-blockers also may be used in children and adolescents with symptomatic HCM.

What should you not do with hypertrophic cardiomyopathy? ›

Don't do street drugs (cocaine and methamphetamines are extremely dangerous for HCM patients) Don't take diet pills or over-the-counter cold medications. Avoid hot tubs and saunas. Be sure to keep regular appointments with your cardiologist to monitor your condition.

What makes hypertrophic cardiomyopathy worse? ›

If the thickened heart muscle blocks the blood flow leaving the heart, the valve between the left atrium and left ventricle (mitral valve) might not close properly. As a result, blood can leak backward into the left atrium (mitral valve regurgitation), possibly making symptoms worse.

Which beta blocker is best for HCM? ›

Of these, metoprolol is most widely used for HCM.
Some of the beta blockers used for heart problems are:
  • Acebutolol (Sectral)
  • Atenolol (Tenormin)
  • Bisoprolol (Zebeta)
  • Metoprolol (Lopressor, Toprol XL)
  • Nadolol (Corgard)
  • Nebivolol (Bystolic)
  • Propranolol (Inderal, InnoPran XL)

How do you improve hypertrophic cardiomyopathy? ›

These lifestyle changes can help improve symptoms and prevent the condition from worsening.
  1. Exercise as Recommended. Regular exercise reduces heart rate and blood pressure and provides overall health benefits. ...
  2. Monitor Blood Pressure. ...
  3. Eat Healthfully. ...
  4. Limit Alcohol Consumption. ...
  5. Control Diabetes. ...
  6. Manage Stress. ...
  7. Quit Smoking.

How can I strengthen my heart with cardiomyopathy? ›

Lifestyle Changes for Cardiomyopathy & Heart Failure
  1. Eat Healthfully. Eating a variety of fruits, vegetables, and whole grains and choosing lean meats and fish can help improve your heart health. ...
  2. Stay Active. ...
  3. Monitor Blood Pressure. ...
  4. Monitor Weight. ...
  5. Control Diabetes. ...
  6. Quit Smoking. ...
  7. Limit Alcohol Consumption. ...
  8. Manage Stress.

Is walking good for HCM? ›

Specialists agree that exercise is healthy for people with HCM. Depending on symptoms, most people with HCM can safely do light exercise like walking. But the HCM experts usually advise people with symptomatic HCM not to do heavy exercise.

Should I exercise with HCM? ›

“I usually encourage my patients with HCM to take up a habitual, moderate-intensity exercise regimen, such as walking a minimum of 20 minutes, 5 days a week,” says Dr.

What is the best drugs for cardiomyopathy? ›

Drugs that are used to treat heart failure and dilated cardiomyopathy include:
  • Blood pressure medications. ...
  • Sacubitril/valsartan (Entresto). ...
  • Water pills (diuretics). ...
  • Digoxin (Lanoxin). ...
  • Ivabradine (Corlanor). ...
  • Blood-thinners (anticoagulants).
May 4, 2022

What is the latest treatment for cardiomyopathy? ›

Mavacamten belongs to a new class of drugs called myosin inhibitors. Inside the heart, two proteins called myosin and actin work in tandem to control heart-muscle contractions allowing the heart to pump blood throughout the body.

How fast does hypertrophic cardiomyopathy progress? ›

Although HCM has 4 identified stages [11], patients with HCM can experience a sudden cardiac arrest or the disease can slowly progress over several years.

Does a pacemaker help hypertrophic cardiomyopathy? ›

A pacemaker is also commonly recommended for people who have very slow heart rates, generally less than 48 beats per minute, as a result of HCM slowing the generation of heart beats.

What foods to avoid if you have hypertrophic cardiomyopathy? ›

Foods to Limit or Avoid:
  • Alcohol.
  • Foods and beverages high in added sugars.
  • Salt and foods high in sodium (discuss with your healthcare provider before strictly limiting)
  • Deep-fried or greasy foods.
  • High fat cuts of red meat.
  • Processed meats.
  • Foods high in saturated fat.
  • Foods with trans fats.
May 26, 2022

What 3 things can you do to avoid cardiomyopathy? ›

You can help reduce your risk of cardiomyopathy and other types of heart disease by living a heart-healthy lifestyle, including:
  • Avoiding the use of alcohol or cocaine.
  • Controlling high blood pressure, high cholesterol and diabetes.
  • Eating a healthy diet.
  • Getting regular exercise.
  • Getting enough sleep.
  • Reducing your stress.
Apr 2, 2022

How do you slow down cardiomyopathy? ›

Your health care professional also may recommend other lifestyle changes, such as:
  1. Quitting smoking.
  2. Losing excess weight.
  3. Avoiding alcohol and illegal drugs.
  4. Getting enough sleep and rest.
  5. Reducing stress.
  6. Treating underlying conditions, such as diabetes and high blood pressure.
May 5, 2022

Does hypertrophic cardiomyopathy get worse with age? ›

Once hypertrophy appears, there is rarely a significant change in muscle thickness in the years of adult life. Other aspects of the heart may change over time including condition of the mitral valve, degree of obstruction, and left atrial size.

Can you fly with HCM? ›

According to expert guidance from the British Cardiovascular Society, most people with heart and circulatory disease can travel by air safely without risking their health.

Can stress make hypertrophic cardiomyopathy worse? ›

Emotional stress leads to autonomic[6,7] and hemodynamic[6,8] changes such as increased contractility and decreased ejection time, which, in turn, may worsen myocardial function in patients with HCM,[9,10] suggesting that emotion could increase symptoms of dyspnea and chest pain in these individuals.

What is the best blood pressure medication for hypertrophic cardiomyopathy? ›

Verapamil is the most widely used calcium channel blocker for HCM patients. It improves the filling of the heart. Like beta-blockers, it can reduce symptoms such as chest pain, shortness of breath, and palpitations. Diltiazem is often used for HCM patients as well.

What medication relaxes heart muscle? ›

Nitroglycerin tablets, often taken for angina, are a vasodilator. These medications help relax the blood vessels and increase the supply of oxygen-rich blood to the heart, also reducing the heart's workload. Some other names for vasodilators are minoxidil and hydralazine.

Which diuretic is used for hypertrophic cardiomyopathy? ›

Three examples used a lot in HCM are furosemide (Lasix), bumetanide (Bumex), and torsemide (Demadex). These drugs are used frequently for heart failure. Thiazide diuretics are probably not used as often in HCM. They are especially useful for treating hypertension.

Can exercise reverse hypertrophic cardiomyopathy? ›

Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy. Circ Res 2006;98:540-8.

How do you reverse thickened heart muscle? ›

There is no treatment which can reverse the changes of the heart muscle. Treatment aims to ease symptoms if they occur and to prevent complications. If you do not have any symptoms or you only have mild symptoms then you may not need any treatment.

How do you heal cardiomyopathy naturally? ›

Six natural remedies for cardiomyopathy symptoms include eating a heart-healthy diet, controlling contributing conditions (like high blood pressure, high cholesterol and diabetes), exercising and maintaining a healthy weight, sleep and stress management, avoiding alcohol, smoking and illegal drugs as well as natural ...

What is the best exercise for cardiomyopathy? ›

Choose an aerobic activity that you enjoy such as walking (outside or on a treadmill), stationary cycling, swimming, and rowing or water aerobics. Ask your doctor before lifting weights. Exercise should be done regularly to gain the benefits; national guidelines suggest most days of the week if not everyday.

What is the best exercise to strengthen your heart? ›

Examples: Brisk walking, running, swimming, cycling, playing tennis and jumping rope. Heart-pumping aerobic exercise is the kind that doctors have in mind when they recommend at least 150 minutes per week of moderate activity.

What is the most common treatment for cardiomyopathy? ›

Treatment options for cardiomyopathy
  • Lifestyle changes. Stopping alcohol use. Monitoring salt intake.
  • Medicines. Lower blood pressure. ...
  • Surgically implanted device that helps maintain proper heart rhythm.
  • Ablation procedure. Removes extra heart tissue to reduce thickening. ...
  • Heart transplant (for a severely damaged heart)

What cardiologist treats cardiomyopathy? ›

Clinical cardiologists: Clinical cardiologists can diagnose, confirm and manage heart disease.

Is hypertrophic cardiomyopathy a serious heart condition? ›

HCM can lead to many serious health conditions, such as: Atrial fibrillation, a type of arrhythmia that can cause blood clots. Heart failure. Stroke.

Is hypertrophic cardiomyopathy considered heart failure? ›

By definition, HCM is a form of heart failure: the heart does not work normally, and the stiffness of the left ventricle means that the output of blood is generally not enough. But HF is often used to mean something a bit narrower: the heart does not pump adequately, and as a result, fluid accumulates in the body.

Will an EKG show hypertrophic cardiomyopathy? ›

The ECG is abnormal in over 90 percent of patients with hypertrophic cardiomyopathy. The most common abnormalities are left ventricular hypertrophy, ST-segment alterations, T-wave inversion, large Q waves and the peculiar diminution of R waves in the lateral precordial leads seen in this patient.”

What is the lifespan of HCM patients? ›

Indeed, the vast majority of patients with HCM have normal life expectancy without incurring any significant limiting symptoms or adverse disease complications.

What is the most common cause of death for patients with hypertrophic cardiomyopathy? ›

HCM can lead to sudden cardiac death (SCD), mainly due to ventricular tachyarrhythmia or ventricular tachycardia.

Can you live a normal life with hypertrophic cardiomyopathy? ›

The good news is that most people have no or minimal symptoms throughout their life and even for those with symptoms, most people with HCM can lead a normal life with treatment and follow-up.

What is the prognosis for hypertrophic cardiomyopathy? ›

Indeed, the vast majority of patients with HCM have normal life expectancy without incurring any significant limiting symptoms or adverse disease complications. However, a small number of patients with HCM are at risk for adverse disease-related events, including heart failure and sudden death.

Does stress affect hypertrophic cardiomyopathy? ›

Excessive stress can raise your blood pressure, which can increase the risk of cardiomyopathy.

How often should I be checked for hypertrophic cardiomyopathy? ›

If you have hypertrophic cardiomyopathy (HCM), the Center for Heart Failure recommends that your first-degree adult relatives (parents, siblings and children) be screened by seeing a physician and getting an electrocardiogram (ECG) and echocardiogram every five years.

Can you be misdiagnosed with hypertrophic cardiomyopathy? ›

Because none of these symptoms is unique to HCM, the condition is often misdiagnosed as exercise-induced asthma, mitral valve prolapse, or anxiety/depression.


1. 2020 ACC guidelines for management of Hypertrophic Cardiomyopathy (HCM)
(Ahmed Mohsen)
2. Hypertrophic Cardiomyopathy: New Guidelines, New Insights, and Next Steps
(Yale Cardiovascular Medicine Grand Rounds)
3. Making Strides in Hypertrophic Cardiomyopathy: Guidelines, Science, and Strategies
(PeerView CME)
4. Living With HCM: Listen to Your Body | CardioSmart
(American College of Cardiology)
5. What is Hypertrophic Cardiomyopathy
6. Hypertrophic Cardiomyopathy
(Health4TheWorld Academy Videos Channel)


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